Meet Your NIH Rigor & Reproducibility Requirements

WiCell’s Short Tandem Repeat (STR) and Karyotype tests can be used to address the NIH’s new grant application guidance regarding the authentication of key biological resources. 


Key take-aways from NIH’s blog post on "Scientific Rigor" published January 29, 2016, by the NIH Deputy Director for Extramural Research include:
  • “Key cell lines might be authenticated by chromosomal analysis or short tandem repeat (STR) profiling.”

  • “Include a plan to independently verify the identity and activity of the product before use.” 

  • “If the product will be used long-term, consider the stability of the product and how the validity of the product will be assessed over time.”

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Image of karyogram and STR profile with cell culture dish