MEET YOUR NIH RIGOR & REPRODUCIBILITY REQUIREMENTS
According to the NIH, the cornerstones of science advancement are rigor in designing and performing scientific research and the reproducibility of biomedical research findings.’
A 2015 study by the journal Nature found that poor materials made the largest contribution to reproducibility problems, at 36%, followed by study design at 28% and data analysis at 26%. The team estimates the overall rate of irreproducibility at 53%, but cautions that the true rate could be anywhere between 18% and 89%. That puts the potential economic cost of irreproducibility anywhere from $10 billion to $50 billion per year.
A 2015 study by the journal Nature found that poor materials made the largest contribution to reproducibility problems, at 36%, followed by study design at 28% and data analysis at 26%. The team estimates the overall rate of irreproducibility at 53%, but cautions that the true rate could be anywhere between 18% and 89%. That puts the potential economic cost of irreproducibility anywhere from $10 billion to $50 billion per year.
How does WiCell address this issue in the scientific community?
- WiCell offers cell lines with release testing that follows best practice in the research process.
- WiCell offers best-practice services that will help you and your lab ensure that your time and research dollars are not wasted!
- WiCell’s Short Tandem Repeat (STR) and Karyotype tests can be used to address the NIH’s new grant application guidance regarding the authentication of key biological resources.
Key take-aways from NIH’s blog post on "Scientific Rigor" published January 29, 2016, by the NIH Deputy Director for Extramural Research include:
- “Key cell lines might be authenticated by chromosomal analysis or short tandem repeat (STR) profiling.”
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“Include a plan to independently verify the identity and activity of the product before use.”
- “If the product will be used long-term, consider the stability of the product and how the validity of the product will be assessed over time.”
Get started today:
Contact WiCell's Characterization Team for a consultation on authentication plans, including adequacy, frequency of testing, and pricing information.Review WiCell's Sample Submission Requirements and Instructions.
