This reporter cell line is a modified version of WA01 (H1), engineered to knock-in MYH11 alleles tagged with NanoLuc-2A-tdTomato. This cell line can be used for smooth muscle cell differentiation and screening of intimal hyperplasia inhibitors.
- Cell Line Alias MYH11-NLuc-tdTomato
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Male
- Genetic Modification Keyword Reporter; Vascular - Smooth Muscle Cells
- Disease None reported
- Genetic Alteration Mutation MYH11
- Pubmed Abstract Zhang, J et al. 'A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia.' Stem Cell Reports 12 (2019): 1269-1281.
- hPSCReg ID WAe001-A-1X
- NIH Approval NIHhESC-10-0043
- Provider -
- Collections Uncategorized
Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
WB68133 | TeSR-E8/Cultrex | WiCell | 32 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |