Powered by Bioz** This cell line contains an expected karyotypic abnormality consistent with the deposited material. Please see the karyotype report in the Product Information & Testing PDF(s) linked below for more information.
An additional clone from this iPS cell line (HVRDi001-A-1) is available from WiCell.
- Cell Line Alias fAD1, fAD 1B, hFAD-1 clone b, fAD-1B
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Male
- Age at Collection 57 Years
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Skin
- Disease Familial Alzheimer`s disease
- Genetic Alteration Mutation APPV717l mutation
- Pubmed Abstract Muratore CR et al "The familial Alzheimer`s disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons." Human Molecular Genetics 23(13) (2014): 3523-3536.
- Genetically related cell lines Yes
- hPSCReg ID HVRDi001-A-1
- Provider Brigham and Women`s Hospital - Dr.Tracy Young-Pearse
- Collections Uncategorized
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
| WB66254 | mTeSR1/Matrigel | WiCell | 31 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |