Powered by BiozThis reporter cell line is a modified version of WC007i-FX13-2 engineered to knock in a Nano-luciferase gene into the endogenous human FMR1 gene. This reporter cell line detects FMR1 gene reactivation in human neural cells and can be a valuable resource to identify novel compounds for FMR1 gene reactivation studies.
- Cell Line Alias FX-iPSC-Nluc1
- Unit of Measure (UOM) vial
- Cell Type Modified Human iPS
- Sex Male
- Age at Collection 8 Years
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Skin
- Genetic Modification Keyword Reporter; Neural
- Disease Fragile X syndrome
- Genetic Alteration Mutation FMR1
- Pubmed Abstract Li, M. et al. "Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells" Stem Cells 35.1 (2017): 158-169.
- Provider University of Wisconsin - Dr. Anita Bhattacharyya and Dr. Xinyu Zhao
- Collections Uncategorized
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
| WB67008 | TeSR-E8/Matrigel | WiCell | 40 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Info URL |
| WB66443 | TeSR-E8/Matrigel | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol |