**Upon testing, the current lot of material did not meet WiCell`s standards for quality, and it is therefore unavailable. WiCell is working with the Provider to obtain replacement materials for distribution. To be notified of the status of this cell line please submit your information here.
- Cell Line Alias SS4-1
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Male
- Age at Collection 30 Years
- Ethnicity Information Physician reported
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Blood
- Genetic Alteration Mutation Information A>T mutation in beta globin gene
- Diagnosis Information Diagnosis of Sickle Cell Anemia SS was physician reported
- Disease Sickle cell anemia SS
- Ethnicity African American
- Genetic Alteration Mutation HBB(E6V)
- Pubmed Abstract Park Seonmi, et al "A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells." Stem Cell Reports 8(4) (2017): 1076-1085.
- dbGap Data phs001212
- Provider Boston University and Boston Medical Center's Center for Regenerative Medicine (CReM) - Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy
- Collections NHLBI Next Gen - Sickle Cell Anemia (Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy, Boston University and Boston Medical Center's Center for Regenerative Medicine)
Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
DB47980 | Stem Cell Culture Medium (KOSR/MEF) | Provider | 6 | WiCell Feeder Based (MEF) Pluripotent Stem Cell Protocol |