Powered by Bioz** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) “Product Information & Testing”
This cell line is a modified version of WIBR3, engineered to contain a homozygous form of the G2019S mutation in LRRK2 found in approximately 5% of autosomal dominant inherited Parkinson’s Disease (PD) cases.
- Cell Line Alias WIBR3_LRRK2_G2019S_65_Homo
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Female
- Genetic Alteration Mutation Information LRRK2 G2019S, NP_940980.4, p.G2019S/p.G2019S
- Genetic Modification Keyword Isogenic - Parkinson's Disease
- Disease Parkinson's disease
- Genetic Alteration Mutation LRRK2
- hPSCReg ID WIBRe001-A-25
- Provider Albert Einstein College of Medicine
- Collections iSCORE-PD: Isogenic Stem Cell Collection to Research Parkinson’s Disease
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB69026 | iSCORE 01 medium / 2x CF1 MEF | WiCell | 46 | WiCell Feeder Based (MEF) Protocol 01 for Culture of MJFF iSCORE Lines |