This cell line is a modified version of WIBR3, engineered to contain a frameshift mutation in the FBX07 gene. This mutation is associated with severe Parkinson’s Disease (PD) symptoms.
- Cell Line Alias WIBR3_FBXO7_FS_A3-1
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Female
- Genetic Alteration Mutation Information FBXO7 Frameshift, NP_036311.3, p.R498Efs*27/p.R498Efs*27
- Genetic Modification Keyword Isogenic - Parkinson's Disease
- Disease Parkinson's disease
- Genetic Alteration Mutation FBX07
- hPSCReg ID WIBRe001-A-10
- NIH Approval NIHhESC-10-0079
- Provider University of California, Berkeley
- Collections iSCORE-PD: Isogenic Stem Cell Collection to Research Parkinson’s Disease
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB69059 | iSCORE 01 medium / 2x CF1 MEF | WiCell | 50 | WiCell Feeder Based (MEF) Protocol 01 for Culture of MJFF iSCORE Lines |