This cell line is a modified version of WA01 (H1) engineered to knock out the FMR1 gene. Mutations in the FMR1 gene cause Fragile X syndrome. Isogenic cell lines WA01 and H1-FMR1-FLAG are available from WiCell.
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Male
- Genetic Modification Keyword Isogenic; Fragile X syndrome
- Disease None reported
- Genetic Alteration Mutation FMR1 Knockout
- Pubmed Abstract Li, M. et al. ''Identification of FMR1-regulated molecular networks in human neurodevelopment''. Genome Research 30.3 (2020): 361-374.
- hPSCReg ID WAe001-A-50
- Provider University of Wisconsin - Dr. Anita Bhattacharyya and Dr. Xinyu Zhao
- Collections Fragile X syndrome Collection
Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
WB67517 | mTeSR1/Matrigel | WiCell | 40 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |