Powered by BiozUpon testing, the current lot of material did not meet WiCell’s standards for quality, and it is therefore unavailable. WiCell is working with the provider to obtain replacement materials for distribution.
This cell line is a modified version of hIPSC-Tri21-c2-4, engineered to remove the third copy of human chromosome 21. This isogenic control is unaffected. An additional disomic cell line, hiPSC-Di21-c2-4-3, is available from WiCell.
- Cell Line Alias Di C2-4-4
- Unit of Measure (UOM) vial
- Cell Type Modified Human iPS
- Sex Female
- Age at Collection 1 Years
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Sox2, Nanog, Lin28)
- Tissue Origin Skin Fibroblast (AG06872)
- Genetic Modification Keyword Isogenic; Down syndrome, Trisomy 21
- Disease None reported
- Ethnicity Caucasian
- Pubmed Abstract Li, Li B. et al. ''Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells'' Cell Stem Cell 11.5 (2012): 615-619.
- Provider University of Washington - Dr. David Russell
- Collections Down syndrome (Russell) Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
| WB67281 | TeSR-E8/Matrigel | WiCell | 41 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |