** This cell line has an unexpected abnormal karyotype. Please see the karyotype report in the Product Information & Testing PDF(s) linked below for more information.
- Cell Line Alias iPSCORE_59_1
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Female
- Age at Collection 63 Years
- Ethnicity Information Self-reported
- Reprogramming Method Non-integrating (Sendai: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Skin Fibroblast
- Diagnosis Information Diagnosis of Dilated Cardiomyopathy was physician reported as the primary heart diagnosis. Doxorubicin toxicity was also physician reported. The physician also commented there was Chemotherapy induced Dilated Cardiomyopathy and ejection fraction recovered on medical therapy.
- Disease Dilated Cardiomyopathy
- Ethnicity African American
- Pubmed Abstract Panopoulos, AD., et al.''IPSCORE: A Resource of 222 IPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.'' Stem Cell Reports 8(4) (2017): 1086-1100.
- dbGap Data phs000924
- Provider University of California, San Diego - Dr. Kelly Frazer
- Collections NHLBI Next Gen - QT Interval and ECG Cardiac Traits (Dr. Kelly Frazer, University of California San Diego)
Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
WB54168 | mTeSR1/Matrigel | WiCell | 20 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |