Charcot-Marie-Tooth disease Collection
Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders that comprises a group of disorders that affect peripheral nerves. This iPSC collection serves as a model for CMT and consists of both control and CMT2A cell lines. CMT2A is the most common axonal form of CMT caused by mutation in Mitofusin 2 (MFN2). iPSCs were created by reprogramming of two human CMT2A fibroblast lines.
Additional information regarding relationships can be found here.
Cell Line | Cell Line Alias | Cell Type | Disease | Genetic Alteration/Mutation | Sex | Age at Collection | Ethnicity | Genetically Related Cell Lines | dbGaP Data |
---|---|---|---|---|---|---|---|---|---|
WC010i-CMT2A-1.1 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | No | No | |||
WC011i-CMT2A-1.2 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | No | No | |||
WC012i-CMT2A-1.3 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | No | No | |||
WC013i-CMT2A-2.1 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | Yes | No | |||
WC014i-CMT2A-2.2 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | Yes | No | |||
WC015i-CMT2A-2.3 | Human iPS | Charcot-Marie-Tooth disease type 2A | MFN2 | Male | Yes | No | |||
WC016i-CMT2A-3.1 | Human iPS | None reported | Male | Yes | No | ||||
WC017i-CMT2A-3.2 | Human iPS | None reported | Male | Yes | No | ||||
WC018i-CMT2A-3.3 | Human iPS | None reported | Male | Yes | No |