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Charcot-Marie-Tooth disease Collection

Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders that comprises a group of disorders that affect peripheral nerves.  This iPSC collection serves as a model for CMT and consists of both control and CMT2A cell lines.  CMT2A is the most common axonal form of CMT caused by mutation in Mitofusin 2 (MFN2).  iPSCs were created by reprogramming of two human CMT2A fibroblast lines.

Additional information regarding relationships can be found here.
Cell Lines 9 Cell Lines
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Cell Line Cell Line Alias Cell Type Disease Genetic Alteration/Mutation Sex Age at Collection Ethnicity Genetically Related Cell Lines dbGaP Data
WC010i-CMT2A-1.1   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     No No
WC011i-CMT2A-1.2   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     No No
WC012i-CMT2A-1.3   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     No No
WC013i-CMT2A-2.1   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     Yes No
WC014i-CMT2A-2.2   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     Yes No
WC015i-CMT2A-2.3   Human iPS Charcot-Marie-Tooth disease type 2A  MFN2  Male     Yes No
WC016i-CMT2A-3.1   Human iPS None reported    Male     Yes No
WC017i-CMT2A-3.2   Human iPS None reported    Male     Yes No
WC018i-CMT2A-3.3   Human iPS None reported    Male     Yes No
Cell Lines 9 Cell Lines
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