Down Syndrome (Russell) Collection
This collection, deposited by Dr. David Russell from the University of Washington, consists of a parental Down Syndrome (DS) cell line, hIPSC-Tri21-c2-4, and its corrected disomic subclones, hIPSC-Di21-c2-4-3 and hIPSC-Di21-c2-4-4. The third copy of chromosome 21 was removed from the disomic subclones by using a combination of gene targeting and negative selection.
Cell Line 
|
Cell Line Alias
|
Cell Type
|
Disease | Genetic Alteration/Mutation |
Sex
|
Age at Collection
|
Ethnicity | Genetically Related Cell Lines |
dbGaP Data
|
|---|---|---|---|---|---|---|---|---|---|
| hIPSC-Di21-c2-4-3 | Di C2-4-3 | Modified Human iPS | None reported | Female | 1 Years | Caucasian | No | No | |
| hIPSC-Di21-c2-4-4 | Di C2-4-4 | Modified Human iPS | None reported | Female | 1 Years | Caucasian | No | No | |
| hIPSC-Tri21-c2-4 | Tri C2-4 | Human iPS | Down syndrome, Trisomy 21 | 47,XX,+21 (Trisomy 21) | Female | 1 Years | Caucasian | No | No |
