Down Syndrome (Russell) Collection

This collection, deposited by Dr. David Russell from the University of Washington, consists of a parental Down Syndrome (DS) cell line, hIPSC-Tri21-c2-4, and its corrected disomic subclones, hIPSC-Di21-c2-4-3 and hIPSC-Di21-c2-4-4.  The third copy of chromosome 21 was removed from the disomic subclones by using a combination of gene targeting and negative selection.

Cell Lines 3 Cell Lines
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Cell Line Cell Line Alias Cell Type Disease Genetic Alteration/Mutation Sex Age at Collection Ethnicity Genetically Related Cell Lines dbGaP Data
hIPSC-Di21-c2-4-3 Di C2-4-3 Modified Human iPS None reported    Female 1 Years Caucasian  No No
hIPSC-Di21-c2-4-4 Di C2-4-4 Modified Human iPS None reported    Female 1 Years Caucasian  No No
hIPSC-Tri21-c2-4 Tri C2-4 Human iPS Down syndrome, Trisomy 21  47,XY,+21 (Trisomy 21)  Female 1 Years Caucasian  No No
Cell Lines 3 Cell Lines
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