** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) Product Information & Testing PDF(s) linked below for more information.

This induced pluripotent stem (iPS) cell line, which serves as a model for Down Syndrome (Trisomy 21) was created by reprogramming a trisomy of 21 (Ts21) human fibroblast line. This isogenic control is unaffected, meaning that it does not carry a third copy of human chromosome 21 (HSA21).
Cell Line Alias DS2U
Cell Type Modified Human iPS
Disease None reported
Genetic Modification Keyword Isogenic; Down syndrome, Trisomy 21
Sex Male
Age at Collection 1 Years
Genetically Related Cell Lines  
Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
Provider University of Wisconsin - Dr. Anita Bhattacharyya
dbGaP Data  
Eagle-I UID  
hPSCReg ID  
NIH Approval  
Pub Med Abstract  
Related Products
Collection(s) Down syndrome (Bhattacharyya) Collection
Have you received this cell line previously? Yes No Why we ask
Quantity: Learn about our volume discounts

Current Lot Information

Lot Number Culture Platform Lot Description Passage Number Banked By Protocol Product Information & Testing
WB17714 mTeSR™1/Matrigel™   66 WiCell WiCell Feeder Independent mTeSR™1 Protocol PDF