UWWC1-DS2U
** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) ``Product Information & Testing`` PDF(s) linked below for more information.
This cell line is a modified version of a trisomy 21 (Ts21) human fibroblast line engineered to remove the third copy of human chromosome 21 (HSA21). This isogenic control is unaffected.
Cell Line Alias
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DS2U |
Cell Type
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Modified Human iPS |
Disease
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None reported |
Genetic Modification Keyword
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Isogenic; Down syndrome, Trisomy 21 |
Sex
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Male |
Age at Collection
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1 Years |
Genetically Related Cell Lines
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Reprogramming Method
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Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
Provider
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University of Wisconsin - Dr. Anita Bhattacharyya
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Related Products
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Collection(s)
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Down syndrome (Bhattacharyya) Collection
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