UWWC1-DS2U
** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) ``Product Information & Testing`` PDF(s) linked below for more information.
This cell line, derived from an individual mosaic for trisomy 21, is an unmodified euploid isogenic control that is disomic for human chromosome 21 (HSA21). This isogenic control is unaffected. Two other clones, affected with trisomy 21 (UWWC1-DS4, UWWC1-DS1), are available from WiCell.
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Cell Line Alias
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DS2U |
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Cell Type
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Human iPS |
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Disease
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None reported |
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Genetic Modification Keyword
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Isogenic; Down syndrome, Trisomy 21 |
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Sex
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Male |
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Age at Collection
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1 Years |
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Genetically Related Cell Lines
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Reprogramming Method
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Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
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Provider
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University of Wisconsin - Dr. Anita Bhattacharyya
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Related Products
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Collection(s)
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Down syndrome (Bhattacharyya) Collection
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