UWWC1-DS4
** This cell line contains an expected karyotypic abnormality consistent with the phenotype indicated in the "disease" field below. Please see the karyotype report in the Product Information & Testing PDF(s) linked below for more information.
This cell line, derived from an individual mosaic for trisomy 21, is a trisomy 21 clone. An additional trisomy 21 clone (UWWC1-DS1) and unmodified isogenic diploid control cell line, UWWC1-DS2U, are available from WiCell.
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Cell Line Alias
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DS4 |
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Cell Type
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Human iPS |
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Disease
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Down syndrome, Trisomy 21 |
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Genetic Alteration/Mutation
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47,XY,+21 (Trisomy 21) |
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Sex
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Male |
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Age at Collection
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1 Years |
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Genetically Related Cell Lines
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Reprogramming Method
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Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
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Provider
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University of Wisconsin - Dr. Anita Bhattacharyya
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Related Products
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Collection(s)
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Down syndrome (Bhattacharyya) Collection
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