This cell line is a patient-derived PTEN Hamartoma Tumor Syndrome (PHTS) line; a clone with variant not corrected during CRISPR process. A CRISPR-corrected isogenic control iPSC line, BCHi013-A-3, is available from WiCell.
- Cell Line Alias HNDS0143-01#A CNC21(+/-)
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Female
- Age at Collection 8 years
- Ethnicity Information England. Physician reported
- Reprogramming Method Non-Integrating (Sendai: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Peripheral Blood Mononuclear Cell
- Genetic Alteration Mutation Information c.277C>G; p.His93Asp
- Genetic Modification Keyword Isogenic - PTEN Hamartoma Tumor Syndrome (PHTS)
- Disease PTEN Hamartoma Tumor Syndrome (PHTS)
- Genetic Alteration Mutation PHTS (heterozygous)
- hPSCReg ID BCHi013-A-1
- Provider Boston Children's Hospital - Dr. Elizabeth Buttermore
- Collections PTEN Hamartoma Tumor Syndrome (PHTS) Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| DB68699 | StemFlex/Matrigel | Provider | 19 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |