Powered by Bioz** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) “Product Information & Testing” PDF(s) linked below for more information.
- Cell Line Alias BR-SP-39-1
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Male
- Age at Collection 22 Years
- Ethnicity Information Physician reported; Country of Origin: Brazil
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Blood
- Genetic Alteration Mutation Information A>T mutation in beta globin gene
- Diagnosis Information Diagnosis of Sickle Cell Anemia SS was physician reported
- Disease Sickle cell anemia SS
- Ethnicity Latino > South American
- Genetic Alteration Mutation HBB(E6V)
- Pubmed Abstract Park Seonmi, et al "A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells." Stem Cell Reports 8(4) (2017): 1076-1085.
- dbGap Data phs001212
- Provider Boston University and Boston Medical Center's Center for Regenerative Medicine (CReM) - Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy
- Collections NHLBI Next Gen - Sickle Cell Anemia (Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy, Boston University and Boston Medical Center's Center for Regenerative Medicine)
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
| WB67703 | mTeSR Plus/Matrigel | WiCell | 14 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Info URL |
| DB66775 | mTeSR1/Matrigel | Provider | WiCell Feeder Independent Pluripotent Stem Cell Protocol |