Powered by BiozThis cell line is a modified version WIBR3, engineered to contain a PRKN Exon 3 deletion which is frequently seen in familial Parkinson’s Disease (PD) cases with PRKN mutations. This mutation is the most frequent cause of autosomal-recessive PD.
- Cell Line Alias WIBR3_PRKN_X3DEL_F2-5
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Female
- Genetic Alteration Mutation Information PRKN Exon 3 Deletion, NP_004553.2, p.N58Qfs*39/p.N58Qfs*39
- Genetic Modification Keyword Isogenic - Parkinson's Disease
- Disease Parkinson's disease
- Genetic Alteration Mutation PRKN
- hPSCReg ID WIBRe001-A-5
- NIH Approval NIHhESC-10-0079
- Provider University of California, Berkeley
- Collections iSCORE-PD: Isogenic Stem Cell Collection to Research Parkinson’s Disease
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB68992 | iSCORE 01 medium / 2x CF1 MEF | WiCell | 30 | WiCell Feeder Based (MEF) Protocol 01 for Culture of MJFF iSCORE Lines |