Powered by Bioz** This cell line has an unexpected abnormal karyotype. Please see the karyotype report in the “Product Information & Testing” PDF(s) linked below for more information.
This cell line is a modified version of hIPSC-Tri21-c2-4, engineered to remove the third copy of human chromosome 21. This isogenic control is unaffected. An additional disomic cell line, hIPSC-Di21-c2-4-4, is available from WiCell.
- Cell Line Alias Di C2-4-3
- Unit of Measure (UOM) vial
- Cell Type Modified Human iPS
- Sex Female
- Age at Collection 1 Years
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Sox2, Nanog, Lin28)
- Tissue Origin Skin Fibroblast (AG06872)
- Genetic Modification Keyword Isogenic; Down syndrome, Trisomy 21
- Disease None reported
- Ethnicity Caucasian
- Pubmed Abstract Li, Li B. et al. ''Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells'' Cell Stem Cell 11.5 (2012): 615-619.
- Provider University of Washington - Dr. David Russell
- Collections Down syndrome (Russell) Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB67215 | Stem Cell Culture Medium (KOSR/MEF) | WiCell | 41 | WiCell Feeder Based (MEF) Pluripotent Stem Cell Protocol |