An additional clone from this iPS cell line (PENN150i-M7-9) is available from WiCell.
**Upon testing, the current lot of material did not meet WiCell`s standards for quality, and it is therefore unavailable. WiCell is working with the Provider to obtain replacement materials for distribution. To be notified of the status of this cell line please submit your information here.
- Cell Line Alias iPS-M7-SeV16
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Male
- Age at Collection 60 Years
- Ethnicity Information Self-reported
- Reprogramming Method Non-Integrating - Sendai > Non-integrating (Sendai: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Blood / PBMC > Blood
- Genetic Alteration Mutation Information Zygosity homozygous, Allele1 p.R46G, Allele 2p.R46G
- Diagnosis Information Diagnosis of Abetalipoproteinemia was physician reported. Age at diagnosis was 9 Years of age (symptoms since birth). Additional diagnosis of kidney stones, blindness, and quadriplegia were also reported.
- Disease Abetalipoproteinemia
- Ethnicity Caucasian
- Genetic Alteration Mutation MTP(R46G)
- Provider University of Pennsylvania - Dr. Daniel Rader
- Collections NHLBI Next Gen - Lipid Conditions (Dr. Daniel Rader, University of Pennsylvania)
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| DB36290 | Stem Cell Culture Medium (KOSR/MEF) | Provider | 39 | WiCell Feeder Based (MEF) Pluripotent Stem Cell Protocol |