Powered by BiozThe karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) “Product Information & Testing” PDF(s) linked below for more information.
This cell line, derived from an individual mosaic for trisomy 21, is an unmodified euploid isogenic control that is disomic for human chromosome 21 (HSA21). This isogenic control is unaffected. Two other clones, affected with trisomy 21 (UWWC1-DS4, UWWC1-DS1), are available from WiCell.
- Cell Line Alias DS2U
- Unit of Measure (UOM) Vial
- Cell Type Human iPS
- Sex Male
- Age at Collection 1 Years
- Reprogramming Method Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc)
- Genetic Modification Keyword Isogenic; Down syndrome, Trisomy 21
- Disease None reported
- Pubmed Abstract Weick, JP et al. "Deficits in Human Trisomy 21 iPSCs and Neurons" PNAS 110.24 (2013): 9962-7
- Provider University of Wisconsin - Dr. Anita Bhattacharyya
- Collections Down syndrome (Bhattacharyya) Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB67907 | mTeSR Plus/Matrigel | WiCell | 55 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Information & Testing |
| WB17714 | mTeSR1/Matrigel | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol | ||
| WB19012 | mTeSR1/Matrigel | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol |