Powered by BiozThis cell line, which serves as a model for Amyotrophic lateral sclerosis (ALS) has an isogenic control (WC035i-SOD1-D90D) available from WiCell.
- Unit of Measure (UOM) vial
- Cell Type Human iPS
- Sex Female
- Age at Collection 50 Years
- Ethnicity Information Self-reported
- Reprogramming Method Non-integrating (Sendai: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Fibroblasts
- Diagnosis Information Amyotrophic lateral sclerosis was physican reported. Age of onset was 44 years. Age at diagnosis was 46 years.
- Disease Amyotrophic lateral sclerosis
- Ethnicity Caucasian
- Genetic Alteration Mutation SOD1 > D90A
- Pubmed Abstract Chen et al "Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons" Cell Stem Cell. 14(6) (2014): 796-809.
- Provider University of Wisconsin - Dr. Su-Chun Zhang
- Collections Amyotrophic lateral sclerosis Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB67762 | mTeSR Plus/Matrigel | WiCell | 20 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Information & Testing |
| WB66734 | mTeSR1/Matrigel | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol |