Powered by BiozThis cell line is a modified version of WC034i-SOD1-D90A, engineered to correct the D90A mutation. This isogenic control is unaffected. An unmodified, affected, isogenic cell line, WC034i-SOD1-D90A, is available from WiCell.
- Unit of Measure (UOM) vial
- Cell Type Modified Human iPS
- Sex Female
- Age at Collection 50 Years
- Ethnicity Information Self-reported
- Reprogramming Method Non-integrating (Sendai: Oct4, Klf4, Sox2, cMyc)
- Tissue Origin Fibroblasts
- Genetic Modification Keyword Isogenic; Amyotrophic lateral sclerosis
- Disease None reported
- Ethnicity Caucasian
- Genetic Alteration Mutation SOD1 > D90A Corrected
- Pubmed Abstract Chen et al "Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons" Cell Stem Cell. 14(6) (2014): 796-809.
- Provider University of Wisconsin - Dr. Su-Chun Zhang
- Collections Amyotrophic lateral sclerosis Collection
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Info URL |
| WB67763 | mTeSR Plus/Matrigel | WiCell | 26 | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Info URL |
| WB66755 | mTeSR1/Matrigel | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol |