** Karyotype reported from a limited analysis. All analyzable metaphase cells were evaluated. See karyotype report in the Product Information & Testing PDF for more information.
This cell line is a modified version of WIBR3, engineered to contain a point mutant (A30P) in the α-Synuclein gene. This mutation has been linked to autosomal dominant early onset Parkinson’s Disease (PD).
- Cell Line Alias WIBR3_SNCA_A30P_A2-3
- Unit of Measure (UOM) vial
- Cell Type Modified Human ES
- Sex Female
- Genetic Alteration Mutation Information SNCA A30P, NP_000336.1, p.A30P/WT
- Genetic Modification Keyword Isogenic - Parkinson's Disease
- Disease Parkinson's disease
- Genetic Alteration Mutation SNCA
- hPSCReg ID WIBRe001-A-7
- Provider University of California, Berkeley
- Collections iSCORE-PD: Isogenic Stem Cell Collection to Research Parkinson’s Disease
| Lot Number | Culture Platform | Lot Description | Banked By | Passage Number | Protocol | Product Information & Testing |
| WB68804 | iSCORE 01 medium / 2x CF1 MEF | WiCell | 42 | WiCell Feeder Based (MEF) Protocol 01 for Culture of MJFF iSCORE Lines |