CREM055i-BR37-1
**Upon testing, the current lot of material did not meet WiCell’s standards for quality, and it is therefore unavailable. WiCell is working with the Provider to obtain replacement materials for distribution. To be notified of the status of this cell line please submit your information here.| Cell Line Alias | BR-SP-37-1 |
| Cell Type | Human iPS |
| Disease | Sickle cell anemia SS |
| Diagnosis Information | Diagnosis of Sickle Cell Anemia SS was physician reported |
| Genetic Alteration/Mutation | HBB(E6V) |
| Genetic Alteration/Mutation Information | A>T mutation in beta globin gene |
| Sex | Female |
| Age at Collection | 20 Years |
| Ethnicity | Latino > South American |
| Ethnicity Information | Physician reported; Country of Origin: Brazil |
| Genetically Related Cell Lines | |
| Reprogramming Method | Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
| Tissue Origin | Blood |
| Provider | Boston University and Boston Medical Center's Center for Regenerative Medicine (CReM) - Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy |
| dbGaP Data | |
| hPSCReg ID | |
| NIH Approval | |
| Pub Med Abstract | |
| Collection(s) | NHLBI Next Gen - Sickle Cell Anemia (Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy, Boston University and Boston Medical Center's Center for Regenerative Medicine) |
Current Lot Information
| Lot Number | Culture Platform | Lot Description | Passage Number | Banked By | Protocol | Product Information & Testing |
|---|---|---|---|---|---|---|
| DB66774 | mTeSR1/Matrigel | 6 | Provider | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
