CREM056i-BR39-1
** The karyotype for this cell line may contain a non-clonal finding known to be recurrent in pluripotent stem cells. Please see the karyotype report in the currently distributing lot(s) ``Product Information & Testing`` PDF(s) linked below for more information.| Cell Line Alias | BR-SP-39-1 |
| Cell Type | Human iPS |
| Disease | Sickle cell anemia SS |
| Diagnosis Information | Diagnosis of Sickle Cell Anemia SS was physician reported |
| Genetic Alteration/Mutation | HBB(E6V) |
| Genetic Alteration/Mutation Information | A>T mutation in beta globin gene |
| Sex | Male |
| Age at Collection | 22 Years |
| Ethnicity | Latino > South American |
| Ethnicity Information | Physician reported; Country of Origin: Brazil |
| Genetically Related Cell Lines | |
| Reprogramming Method | Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
| Tissue Origin | Blood |
| Provider | Boston University and Boston Medical Center's Center for Regenerative Medicine (CReM) - Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy |
| dbGaP Data | |
| hPSCReg ID | |
| NIH Approval | |
| Pub Med Abstract | |
| Collection(s) | NHLBI Next Gen - Sickle Cell Anemia (Dr. Steinberg, Dr. Mostoslavsky, Dr. Murphy, Boston University and Boston Medical Center's Center for Regenerative Medicine) |
Current Lot Information
| Lot Number | Culture Platform | Lot Description | Passage Number | Banked By | Protocol | Product Information & Testing |
|---|---|---|---|---|---|---|
| WB67703 | mTeSR Plus/Matrigel | 14 | WiCell | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
Historical Lot Information
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Information & Testing |
|---|---|---|---|---|---|
| DB66775 | mTeSR1/Matrigel | Provider | WiCell Feeder Independent Pluripotent Stem Cell Protocol |
