UCSD236i-APP1-1
**Upon testing, the current lot of material did not meet WiCell’s standards for quality, and it is therefore unavailable. WiCell is working with the Provider to obtain replacement materials for distribution. To be notified of the status of this cell line please submit your information here.| Cell Line Alias | APP1.1 |
| Cell Type | Human iPS |
| Disease | Familial Alzheimer`s disease |
| Diagnosis Information | Diagnosis of Familial Alzheimer's disease was physician reported. Age of diagnosis was 46 years. |
| Genetic Alteration/Mutation | APP (duplication) |
| Genetic Alteration/Mutation Information | Duplication of the amyloid-beta precursor protein gene. |
| Sex | Male |
| Age at Collection | 51 Years |
| Ethnicity | Caucasian > Nordic |
| Ethnicity Information | Self-reported |
| Genetically Related Cell Lines | |
| Reprogramming Method | Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
| Tissue Origin | Skin |
| Provider | University of California - San Diego, Dr. Larry Goldstein |
| dbGaP Data | |
| hPSCReg ID | |
| NIH Approval | |
| Pub Med Abstract | |
| Collection(s) | Alzheimer's disease |
Current Lot Information
| Lot Number | Culture Platform | Lot Description | Passage Number | Banked By | Protocol | Product Information & Testing |
|---|---|---|---|---|---|---|
| WB66255 | Stem Cell Culture Medium (KOSR/MEF) | 22 | WiCell | WiCell Feeder Based (MEF) Pluripotent Stem Cell Protocol |
Historical Lot Information
| Lot Number | Culture Platform | Lot Description | Banked By | Protocol | Product Information & Testing |
|---|---|---|---|---|---|
| DB26819 | Stem Cell Culture Medium (KOSR/MEF) | Provider | WiCell Feeder Based (MEF) Pluripotent Stem Cell Protocol |
