|
Cell Line Alias
|
Appdp2.3 |
|
Cell Type
|
Human iPS |
|
Disease
|
Familial Alzheimer`s disease |
|
Diagnosis Information
|
Diagnosis of Familial Alzheimer's disease was physician reported. Age of diagnosis was 53 years. |
|
Genetic Alteration/Mutation
|
APP (duplication) |
|
Genetic Alteration/Mutation Information
|
Duplication of the amyloid-beta precursor protein gene. |
|
Sex
|
Female |
|
Age at Collection
|
60 Years |
|
Ethnicity
|
Caucasian > Nordic |
|
Ethnicity Information
|
Self-reported |
|
Genetically Related Cell Lines
|
|
|
Reprogramming Method
|
Viral transfection (Lentivirus: Oct4, Klf4, Sox2, cMyc) |
|
Tissue Origin
|
Skin |
|
Provider
|
University of California - San Diego, Dr. Larry Goldstein
|
|
dbGaP Data
|
|
|
hPSCReg ID
|
|
|
NIH Approval
|
|
|
Pub Med Abstract
|
|
|
Collection(s)
|
Alzheimer's disease
|
