WC-24-02-DS-M
** This cell line contains an expected karyotypic abnormality consistent with the phenotype indicated in the ``disease`` field below. Please see the karyotype report in the ``Product Information & Testing`` PDF(s) linked below for more information.
This cell line, derived from an individual mosaic for trisomy 21, is a trisomy 21 clone. Additional trisomy 21 clones (WC-24-02-DS-O and WC-24-02-DS-P) and unmodified isogenic diploid control cell lines, WC-24-02-DS-A, WC-24-02-DS-B and WC-24-02-DS-C, are available from WiCell.
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Cell Type
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Human iPS |
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Disease
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Down syndrome, Trisomy 21 |
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Genetic Alteration/Mutation
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47,XX,+21 (Trisomy 21) |
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Sex
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Female |
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Age at Collection
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25 Years |
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Ethnicity
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Caucasian |
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Genetically Related Cell Lines
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Reprogramming Method
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Non-Integrating (Episomal Plasmid: Oct4, Klf4, Sox2, cMyc) |
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Tissue Origin
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Skin |
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Provider
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University of Wisconsin - Dr. Anita Bhattacharyya
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dbGaP Data
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hPSCReg ID
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NIH Approval
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Pub Med Abstract
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Collection(s)
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Down syndrome (Bhattacharyya) Collection
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